Infectious Disease

Combat Infectious Disease with
Rapid and Accurate Detection




In recent years, infectious diseases have become more prevalent, more severe, and more difficult to treat. 

Pathogen Detection

Microbial testing has recently moved from cell culture methods to molecular diagnostic methods. Typically, researchers and clinicians are interested in testing for many pathogens at the same time, and increasingly, they want a quantitative answer.

Using the Modaplex System, researchers can very easily assay multiple pathogens in the same sample, and receive a qualitative or quantitative answer depending on the application. Clinical labs use the Modaplex System to develop tests (LDTs) for detection of infectious agents.  

Assays

  • Fungal Panel (direct blood detection)
  • Transplant Panel (multiple viral loads)
  • STI Panel (yeast, virus, bacteria, parasites)
  • Respiratory Panel (pathogens including drug-resistant strains)
  • Food Pathogen
  • Pharma QC

We have performed numerous experiments to demonstrate the capabilities of the Modaplex System in pathogen detection applications such as identification of variant strains and drug resistant pathogens. 

In one such experiment, using our STI panel, we showed that we can simultaneously detect and discriminate seven pathogens (two bacteria, two yeasts, two viruses and one parasite.) Three dual-labeled calibrators (FAM and TYE) were used for peak assignment and sizing and an Internal Control (TYE labeled) was used to monitor PCR inhibition. These results demonstrate that the Modaplex can quantitatively analyze seven separate pathogens from one sample in the same well. 

Learn more about applications that QIAGEN’s multiplex PCR technology supports.